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Do not make use of Lopressor HCT if: you are allergic to any kind of ingredient in Lopressor HCT, to an additional beta-blocker (eg, propranolol), or to a sulfonamide medication (eg, sulfamethoxazole, probenecid, glyburide); you have an extremely slow heart beat, certain kinds of irregular heartbeat (eg, second- or third-degree heart block, unwell sinus disorder), unrestrained heart failing, shock brought on by serious heart troubles, or serious blood circulation issues; you are unable to pee or you are taking dofetilide.